The Carnivore Code by Paul Saladino
Author:Paul Saladino
Language: eng
Format: epub
Publisher: Fundamental Press
Gordon, T. et al., (1977). High density lipoprotein as a protective factor against coronary heart disease: The Framingham study. The American Journal of Medicine, 62(5): 707-714.
We can see why researchers might look at this and believe that there’s a direct relationship between the amount of LDL in the blood and cardiovascular disease: the more total cholesterol and LDL, the more people from this study had cardiovascular events. But a very interesting thing happens to this graph when we separate all of the people studied into groups based on their levels of HDL.
Up to this point we’ve spoken about HDL only briefly when we discussed its role in reverse cholesterol transport. Another very interesting thing about HDL is that its level correlates directly with insulin sensitivity.45,46,47 In those with insulin resistance, HDL levels fall and triglyceride levels rise, a change in blood parameters known as metabolic dyslipidemia.48 Thus, those with the lowest levels of HDL are much more likely to have insulin resistance than those with higher levels of this lipoprotein.49,50 Looking at the graph that follows, it’s immediately apparent that differences in HDL make a huge difference in cardiovascular disease risk. Keep in mind that this is exactly the same data from the Framingham Study depicted in the previous graph, but participants have been split into groups based on their HDL levels.
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