Understanding Evidence-Based Rheumatology by Hasan Yazici Yusuf Yazici & Emmanuel Lesaffre

Author:Hasan Yazici, Yusuf Yazici & Emmanuel Lesaffre
Language: eng
Format: epub
Publisher: Springer International Publishing, Cham

Conclusions

Use of standardized outcome measures in rheumatology increased significantly over the last decade and led to improvements in comparability of clinical studies across different settings and patient care. RA is the condition that drove the development of standardized outcome measures in rheumatology followed by other rheumatologic conditions. Many of the currently used standardized outcome measures in RA (i.e., DAS28, CDAI, SDAI, RAPID3, HAQ) are based on the Core Data Set that includes patient-reported (physical function, pain, patient global estimate of status), physical examination (swollen joint count, tender joint count, physician/assessor patient global estimate of status), and laboratory (ESR or CRP) measures. With increased understanding of the underlying disease processes in RA, there is growing interest in the development of imaging and biomarker-based measures that can be used in conjunction with patient-reported and physical examination measures to improve measurement of disease activity in RA.

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