Thoracic Imaging A Core Review by Hobbs Stephen & Cox Christian

Author:Hobbs, Stephen & Cox, Christian
Language: eng
Format: epub
Publisher: LWW
Published: 2015-08-09T16:00:00+00:00

78a Answer: B.

78b Answer: A.The normal diameter of the main pulmonary artery is approximately 25 mm. The 90th percentile cutoff value is 29 mm in men and 27 mm in women. A measurement of 37 mm, as found in this case, is highly likely to be associated with pulmonary arterial hypertension. A recent meta-analysis showed that pulmonary arterial hypertension was found in about 13% of subjects with scleroderma, compared with 3% of patients with lupus. The prevalence of pulmonary hypertension in subjects with Sögren syndrome and polymyositis–dermatomyositis is low. In patients with scleroderma, the NSIP pattern of lung fibrosis is found in 78% of surgical lung biopsies, substantially more common than other pathologies including UIP.

References: Bouros D, Wells AU, Nicholson AG, et al. Histopathologic subsets of fibrosing alveolitis in patients with systemic sclerosis and their relationship to outcome. Am J Respir Crit Care Med 2002;165(12):1581–1586.

Truong QA, Massaro JM, Rogers IS, et al. Reference values for normal pulmonary artery dimensions by noncontrast cardiac computed tomography: the Framingham Heart Study. Circ Cardiovasc Imaging 2012;5(1):147–154.

Yang X, Mardekian J, Sanders KN, et al. Prevalence of pulmonary arterial hypertension in patients with connective tissue diseases: a systematic review of the literature. Clin Rheumatol 2013;32(10):1519–1531.

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