The Bethesda System for Reporting Thyroid Cytopathology by Syed Z. Ali & Edmund S. Cibas

Author:Syed Z. Ali & Edmund S. Cibas
Language: eng
Format: epub
Publisher: Springer International Publishing, Cham

Fig. 7.2Suspicious for papillary thyroid carcinoma. This loose sheet of follicular cells demonstrates enlarged nuclei, powdery chromatin, nucleoli, and nuclear grooves . There are some questionable (i.e., small, poorly defined) intranuclear pseudoinclusions (arrows) and slight nuclear molding (arrow heads). These changes were patchy, however, and other follicular cells looked entirely benign (ThinPrep, Papanicolaou stain).

The sample is moderately or highly cellular.

Unremarkable follicular cells (arranged predominantly in macrofollicle fragments) are admixed with cells that have nuclear enlargement, nuclear pallor, nuclear grooves, nuclear membrane irregularity, and/or nuclear molding.

Intranuclear pseudoinclusions (INCIs) are very few or absent, and psammoma bodies and papillary architecture are absent. Pattern B ( Incomplete Nuclear Changes Pattern , Fig. 7.3)

Fig. 7.3Suspicious for papillary thyroid carcinoma. In this specimen, there were generalized but mild nuclear changes . A loose sheet of follicular cells shows slightly enlarged nuclei, variable chromatin pallor, small but prominent nucleoli, nuclear grooves, and minimal molding (ThinPrep, Papanicolaou stain).

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