The Active Female by Jacalyn J. Robert-McComb Reid L. Norman & Mimi Zumwalt
Author:Jacalyn J. Robert-McComb, Reid L. Norman & Mimi Zumwalt
Language: eng
Format: epub
Publisher: Springer New York, New York, NY
19.5.1.3 Progesterone
To date, there is no reliable evidence that topical progesterone creams offer protection against bone loss. In a 1999 study, women were randomized to a progesterone cream 20 mg or placebo cream, to be applied once daily. BMD was assessed every 4 months for 1 year and no significant difference was found between the treatment and control groups with respect to BMD of the hip and spine [35]. There is some evidence that norethindrone acetate may maintain BMD in women receiving gonadotropin releasing hormone agonists for conditions such as endometriosis or uterine leiomyomata. Norethindrone acetate or combination estrogen progestin regimens are used for “add-back” therapy in these women primarily to control vasomotor symptoms such as hot flashes.
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