Radiation Oncology Question Review, Second Edition by Michael A. Weller Nikhil Joshi & Anthony Mastroianni

Author:Michael A. Weller, Nikhil Joshi & Anthony Mastroianni
Language: eng
Format: epub
Publisher: Springer Publishing Company
Published: 2018-09-27T16:00:00+00:00

82.The RTOG 97-04 phase III study compared gemcitabine to 5-fluorouracil, before and after concurrent chemoradiation with 5-fluorouracil for patients with resected pancreatic adenocarcinoma. Which group of patients had the highest survival?

Patients with pancreatic head cancers treated with gemcitabine and chemoradiation had a median survival of 20.5 months and a 3-year survival rate of 31% compared with those treated with fluorouracil and chemoradiation, who had a median survival of 16.9 months and a 3-year survival rate of 22% (p = .09).

Regine WF, Winter KA, Abrams RA, et al. Fluorouracil versus gemcitabine chemotherapy before and after fluorouracil-based chemoradiation following resection of pancreatic adenocarcinoma: a randomized controlled trial. JAMA. 2008;299:1019-1026. Regine WF, Winter KA, Abrams RA, et al. Fluorouracil versus gemcitabine chemotherapy before and after fluorouracil-based chemoradiation following resection of pancreatic adenocarcinoma: a randomized controlled trial. JAMA. 2008;299:1019-1026.

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