Obesity, Type 2 Diabetes and the Adipose Organ by Saverio Cinti

Author:Saverio Cinti
Language: eng
Format: epub
Publisher: Springer International Publishing, Cham

PLATE 7.8

Mitochondria II

In cold-acclimated animals, the size of IBAT mitochondria is variable (upper figure). This feature correlates with the possibility of fractioning mitochondria by centrifugation into different subpopulations termed heavy, medium, and light mitochondria. In interscapular BAT brown adipocytes, the smooth endoplasmic reticulum is hypertrophic and is arranged as small networks among mitochondria (arrow in the lower panel of this plate and arrows in Plate 7.7).

Note the dilated area at low density among cristae in the matrix of large mitochondrion in the upper plate (arrow). This dilatation is due to the presence of filamentous structures corresponding to the morphology of mitochondrial DNA.Suggested Reading

Thomson JF, et al. Ultrastructural and biochemical changes in brown fat in cold-exposed rats. J Cell Biol. 41:312–34, 1969.

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