Molecular Surgical Pathology by Liang Cheng & John N. Eble

Author:Liang Cheng & John N. Eble
Language: eng
Format: epub
Publisher: Springer New York, New York, NY

In addition, the importance of epigenetic mechanisms in tumorigenesis has been established

Despite these advances, translation of these findings into clinically relevant and useful applications is still in its early stages

The discovery of the TMPRSS2–ERG rearrangement has been a significant development in the molecular understanding of prostate cancer

TMPRSS2–ETS Gene Fusions

These rearrangements involve fusion of the androgen-regulated gene, TMPRSS2, with a member of one of the ETS family of transcription factors, ERG being the most common; both genes occurring on chromosome 21

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