Inflammatory Dermatopathology by Steven D. Billings & Jenny Cotton

Author:Steven D. Billings & Jenny Cotton
Language: eng
Format: epub
Publisher: Springer US, Boston, MA

•Differentiation of reactive lymphoid infiltrates from low-grade B-cell lymphoma (follicular center, marginal zone) may be quite difficult

•Features that favor lymphoid hyperplasia include the following:

–Polarized germinal centers with tingible body macrophages

–Clinical correlation is paramount to the diagnosis

–“Top-heavy” (superficial and mid-dermal) infiltrate with preservation of adnexal structures,

–Mixed cell infiltrate, B-cells generally limited to germinal centers

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