How Can Physics Underlie the Mind? by George Ellis

Author:George Ellis
Language: eng
Format: epub
Publisher: Springer Berlin Heidelberg, Berlin, Heidelberg

5.6.1.6 Genetic Circuits

Variable components and random lower level processes occur in genetic circuits. According to Eldar and Elowitz [24]:

The genetic circuits that regulate cellular functions are subject to stochastic fluctuations, or ‘noise’, in the levels of their components. Noise, far from just a nuisance, has begun to be appreciated for its essential role in key cellular activities. Noise functions in both microbial and eukaryotic cells, in multicellular development, and in evolution. It enables coordination of gene expression across large regions, as well as probabilistic differentiation strategies that function across cell populations. At the longest timescales, noise may facilitate evolutionary transitions [...] Emerging principles connect noise, the architecture of the gene circuits in which it is present, and the biological functions it enables.

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