Extracellular Vesicles in Cardiovascular and Metabolic Diseases by Junjie Xiao

Author:Junjie Xiao
Language: eng
Format: epub
ISBN: 9789819914432
Publisher: Springer Nature Singapore

9.4 Perspective

EVs are important carriers of signal transduction and material exchange between cells. A large number of studies have revealed the role of EVs in fatty liver and are involved in the occurrence and development of fatty liver. Some EVs have specificity and can be used as biomarkers for clinical diagnosis, disease evaluation, and efficacy testing of fatty liver. Some exosomes can become carriers for drug delivery, so as to achieve specific targeted therapy of fatty liver, which provides a new direction for fatty liver associated research. In addition, EVs also play an important role in the diagnosis of fatty liver. The diagnostic efficacy of specific nucleic acids or proteins in EVs still needs to be verified by large sample clinical studies. In terms of treatment, the large-scale preparation, separation, purification, and preservation methods of EVs are still immature. The mechanism of EVs targeting cells is still unclear, so the communication between cells mediated by EVs is still the focus of future research.

In conclusion, EVs have great potential in the diagnosis, therapy, and prognosis of fatty liver and provide new ideas for the further diagnosis and therapy of fatty liver. It is expected that with the advancement of technology, EVs can achieve clinical transformation as soon as possible and provide a new direction for the diagnosis and therapy of fatty liver.

References

1.

Koch M, Nothlings U, Lieb W (2015) Dietary patterns and fatty liver disease. Curr Opin Lipidol 26(1):35–41PubMed

Download

Copyright Disclaimer:
This site does not store any files on its server. We only index and link to content provided by other sites. Please contact the content providers to delete copyright contents if any and email us, we'll remove relevant links or contents immediately.