ESSENTIALS OF PSYCHIATRY by Jerald Kay

Author:Jerald Kay
Format: epub, pdf
Published: 0101-01-01T00:00:00+00:00

546

Part V Disorders

Table 46.3 Antidepressant Medications Category

Category Side Effects

Trade Name Compound

Usual

Therapeutic

Dose (mg) Sedation

Hypotension (Decreased Blood Pressure)

Anticholinergic Cardiac (i.e., Dry Mouth (Slowed Heart Constipation) Rate)

Tricyclics

Tertiary Amines

Anafranil Clomipramine 150–300 High High High Yes Elavil Amitriptyline 150–300 High High High Yes Sinequan Doxepin 150–300 High Moderate Moderate Yes Surmontil Trimipramine 150–300 High Moderate Moderate Yes Tofranil Imipramine 150–300 Moderate High Moderate Yes Norpramine Desipramine 100–300 Low High Low Yes Pamelor Nortriptyline 50–150 Moderate Low Low Yes Vivactil Protriptyline 20–60 Low Low High Yes

Monoamine

Oxidase Inhibitors

Marplan Isocarboxazid 30–60 Low Moderate Low Low Nardil Phenelzine 45–90 Low Moderate Low Low Parnate Tranylcypromine 30–90 Low Moderate Low Low Atypical Agents

Ascendin Amoxapine 200–300 Low Moderate Low Yes Desyrel Trazodone 300–600 High High Minimal Low Ludiomil Maprotiline 150–200 Moderate Moderate Low Low Wellbutrin Bupropion 150–450 Minimal Low Minimal Yes

Selective Serotonin

Reuptake Inhibitors

Paxil Paroxetine 20–50 Low Minimal Minimal Low Prozac Fluoxetine 20–100 Minimal Minimal Minimal Low Zoloft Sertraline 50–300 Minimal Minimal Minimal Low Luvox Fluvoxamine 150–400 Low Low Low Low Celexa Citalopram 20–50 Minimal None None Minimal Lexapro Escitalopram 10–30 Minimal None None Minimal

Serotonin/

Norepinephrine

Reuptake Inhibitors

Effexor Venlafaxine 75–450 Low None None Minimal

Serotonin

Transport

Blocker and

Antagonist

Serzone Nefazadone 200–600 Minimal Low Minimal Minimal

Alpha-2-

Adrenergic

Antagonist

Remeron Mirtazapine 30–60 Moderate Low Minimal Minimal

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