Drug Allergy by Brian A. Baldo & Nghia H. Pham
Author:Brian A. Baldo & Nghia H. Pham
Language: eng
Format: epub
Publisher: Springer New York, New York, NY
Table 6.3Inhibition of trimethoprim–IgE antibody interactions in the sera of trimethoprim-allergic patients by trimethoprim and some structurally-related compounds
Compound and structure
% Inhibition of IgE antibody binding to TMP–Sepharose with 100 nmol of compound in sera
Group 1
Group 2
Group 3
I1
I2
A1
A2
I3
I4
I5
A3
Trimethoprim
94
96
92
84
91
94
72
49
Diaveridine
76
90
97
85
92
86
3
0
3,4,5-Trimethoxycinnamic acid
87
60
84
40
50
14
10
0
3,4-Dimethoxyphenylethylamine
63
76
93
60
80
24
11
0
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