Clinical Medicine by Bradley John R.; Gurnell Mark; Wood Diana F. & Mark Gurnell & Diana F. Wood

Author:Bradley, John R.; Gurnell, Mark; Wood, Diana F. & Mark Gurnell & Diana F. Wood
Language: eng
Format: epub
Publisher: John Wiley & Sons, Incorporated
Published: 2018-09-11T00:00:00+00:00

Investigation

GBS is predominantly a clinical diagnosis, supported by excluding other diagnoses and demonstrating characteristic findings in tests including:

Electrophysiology: may show dispersed motor potentials and prolonged distal motor latencies; also helps to subclassify as predominantly demyelinating or axonal.

Lumbar puncture: characteristically reveals a high CSF protein (>1 g/l) with no, or very few, white cells – a raised white cell count should prompt consideration of other diagnoses, e.g. human immunodeficiency virus (HIV), Lyme disease, leptomeningeal malignancy.

Antiganglioside antibodies: see earlier.

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