Blood and Marrow Transplant Handbook by Richard T. T. Maziarz & Susan Slater

Author:Richard T. T. Maziarz & Susan Slater
Language: eng
Format: epub
Publisher: Springer New York, New York, NY

c.If patient is sulfa-allergic, alternative therapies include pentamidine 4 mg/kg/day IV (need to renal dose adjust with abnormal renal function) for 21 days (for severe disease) or clindamycin 450 mg po q 6 h with primaquine 15 mg (base) po daily (for mild to moderate disease) for 21 days. Corticosteroids at a dose of 40 mg po BID days 1–5, then 40 mg po daily for days 6–10 and 20 mg po daily for days 11–21 can be considered in combination with antimicrobial therapy if patient not already receiving steroids in comparable dosages in the setting of moderate to severe disease.

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