Biopsy Interpretation: The Frozen Section by Taxy Jerome B

Author:Taxy, Jerome B. [Taxy, Jerome B.; Husain, Aliya N.; Montag]
Language: eng
Format: epub
ISBN: 978-1-4511-8679-6
Publisher: Lippincott Williams & Wilkins
Published: 2014-03-10T16:00:00+00:00

10

HEAD AND NECK

ADRIANA ACURIO AND JEROME B. TAXY

INTRODUCTION

Intraoperative consultation in head and neck cancer management concerns tumor diagnosis, margin evaluation, and nodal status, one or all of which help to determine the extent of surgery. These issues will be addressed here related to conventional mucosal squamous carcinoma and salivary gland tumors, the most common tumors in this anatomic region. The tissue artifacts commonly encountered on frozen sections and the effects of (neo) adjuvant therapy as possible pitfalls in interpretation will also be discussed. In addition, consideration will be given to the relatively recent application of frozen section to the management of acute invasive fungal rhinosinusitis as a guide for surgical debridement, which is an essential part of the therapy for this disease. Studies on the accuracy of frozen section in head and neck cancers suggest it is reliable, with an accuracy rate of 98% and a sensitivity and specificity of 89% and 99%, respectively (1).

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