Bacteria for Breakfast by Kelly Dowhower Karpa

Author:Kelly Dowhower Karpa [Karpa, Kelly]
Language: eng
Format: epub
ISBN: 9781412215411
Publisher: Trafford Publishing
Published: 2008-04-28T04:00:00+00:00

Common Therapies for Inflammatory Bowel Disease

Many different prescription products have been used with varying degrees of success over the years to either treat flare-ups or to try to maintain remission. At the present time, anti-inflammatory agents like 5-aminosalicylates, azathioprine, 6-mercaptopurine, cyclosporine, and prednisone or antibiotics like metronidazole or vancomycin are the main prescription products used to treat inflammatory bowel disease. Interestingly, each of the above mentioned drugs (except for prednisone) has some anti-microbial actions, pointing to the idea that intestinal inflammation is almost certainly related directly or indirectly to a problem with gut bacteria. However, each of these therapies is associated with potential for severe, even life-threatening adverse effects.

Antibiotics offer some benefits in inflammatory bowel disease by (a) reducing the overall numbers of bacteria in the intestine, (b) entirely eliminating specific infectious bacterial populations, (c) diminishing tissue invasion and abscess formation, and (d) preventing bacterial translocation out of the intestines to other parts of the body (Farrell and LaMont, 2002). However, continuous antibiotic therapy also comes with the risk of harmful side effects, antibiotic-resistant microorganisms emerging, and the potential overgrowth of disease-causing strains like Clostridium difficile (Farrell and LaMont, 2002). Additionally, many folks cannot tolerate antibiotics due to allergic reactions.

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