Atlas of Essential Dermatopathology by Kasia S. Masterpol Andrea Primiani & Lyn M. Duncan

Author:Kasia S. Masterpol, Andrea Primiani & Lyn M. Duncan
Language: eng
Format: epub
Publisher: Springer London, London

Scattered mitotic figures at base of epithelium

Often associated with a lichenoid inflammatory infiltrate (lichen planus, lichen sclerosus, lichen simplex chronicus)

Often progresses to HPV-negative SCC Greater potential for progression to invasive SCC than classic VIN

Look for small foci of stromal microinvasion into ­papillary dermis

p53-positive

Fig. 26.1Condyloma Accuminatum. There is a papillomatous acanthosis of the epidermis and hyperkeratosis

Fig. 26.2Vulvar Lichen Planus. There is a lichenoid inflammatory infiltrate, squamatization of basal layer keratinocytes and formation of a large subepidermal cleft, the so-called Max-Joseph space

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