Side Effects of Medical Cancer Therapy by Mario A. Dicato

Author:Mario A. Dicato
Language: eng
Format: epub
Publisher: Springer London, London

Hematologic

Neutropenia has been seen in almost 80 % of patients treated by irinotecan monotherapy; severe neutropenia (<0.5 × 106 G/L) has been seen in 22 % of patients. The hematotoxicity is reversible, with a nadir around the eighth day and subsequent rapid ­recovery. The neutropenia is not cumulative. Anemia is seen in 58 % of patients. Thrombocytopenia is seen less frequently; approximately 10 % of patients will be seen with thrombocytes less than 100 × 106 G/L.

Dermatologic

Reversible alopecia is very common.

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