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Rare Diseases and Orphan Drugs by Berman Jules J

Rare Diseases and Orphan Drugs by Berman Jules J

Author:Berman, Jules J. [Berman, Jules J.]
Language: eng
Format: epub
ISBN: 9780124200098
Publisher: Elsevier Science
Published: 2014-08-15T00:00:00+00:00


Chapter 11

Rare Diseases and Common Diseases: Understanding their Fundamental Differences

Abstract

In Chapter 3, we listed a set of biological properties that distinguish rare diseases from common diseases. In the subsequent chapters, we introduced a number of concepts and experimental discoveries that were relevant to the rare diseases. In this chapter, we revisit the observations listed in Chapter 3, interpreting each observation based on information learned in subsequent chapters. We also introduce the concept of rare diseases hidden within common diseases, and discuss quantitative methods whereby hidden rare diseases can be uncovered.



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