Aging and Lung Disease by Margaret Pisani

Author:Margaret Pisani
Language: eng
Format: epub
Publisher: Humana Press, Totowa, NJ

Menopausal Status as a Risk Factor for OSA

In women, menopausal status is likely a factor, with postmenopausal women being at a much higher risk for OSA than premenopausal women [13]. A cross-sectional study compared the prevalence and severity of OSA between premenopausal (<45 years old) and postmenopausal women (>55 years old) using polysomno­graphy. The prevalence of the OSA was much higher 47% in the postmenopausal group compared to 21% in the premenopausal group. The postmenopausal women had also more severe OSA compared to premenopausal women even after adjusting for body mass index (BMI) and neck circumference [14]. Ware et al. examined the effect of gender and age on the frequency and duration of apneas in patients matched for BMI. The frequency of apneas was not significantly different between young (18–39 years old) and middle aged (40–59 years old) women, but was higher among men. The group with older woman (60–88 years old) had nearly twice as many apneas compared to the young and middle aged groups. The duration of apneas also increased with age, especially in men [15]. In a general population of women aged 50–70 years, chosen at random, the prevalence of sleep-disordered breathing (AHI  ≥  5/h) was also found to be quite high, approaching 30%, but by contrast, the frequency of apneas was not significantly different between men and women [16].

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