Pharmaceutical Powder and Particles by Anthony J. Hickey & Stefano Giovagnoli

Author:Anthony J. Hickey & Stefano Giovagnoli
Language: eng
Format: epub
ISBN: 9783319912202
Publisher: Springer International Publishing

Conclusion

In the previous section, the scientific principles on which particle size measurements are based were reviewed. For these principles to be valuable, they must translate to practical means of sampling and technique of measuring the dimensions. Understanding the limits (particle size range) to the application of any of the methods described is a starting point for their selection in characterizing an unknown particle population. Further the application must be considered since the particle size data will be used to establish quality and performance specifications for the product. Finally, no single method can be trusted to capture all information regarding particle size of relevance to the product. Each method should be used in a complementary fashion with others, and minimally microscopy should be conducted to confirm that indirect methods are accurately reflecting direct observations.

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