Molecular Theory of the Living Cell by Sungchul Ji

Author:Sungchul Ji
Language: eng
Format: epub
Publisher: Springer New York, New York, NY

(d)The similarities among the numbers in Column (4) of Table 11.11 reflect the similarities among the amino acid sequences of the conformons in Column (3). Thus the amino acid sequence constituting the core of conformons belonging to Conformer A (i.e., 35, 60, 100) is more similar in structure (or closer in what may be referred to as the conformon space, an abstract space wherein each point represents one conformon within an enzyme) to Conformon B (i.e., 55, 60, 111) than is Conformon C (i.e., 10, 60, 125), and so are the corresponding p(w) values given in Column (4), i.e., 20 is closer to 18 than is 15. Similar correlations hold between Column (3) and Column (5): The amino acid residues constituting conformons belonging to Conformer A are more tightly centered on (35, 60, 100) than are those constituting the conformons belonging to Conformer C around (10, 60, 125). Consequently, the values of the nondeterministic component of Eq. 11.27 due to the conformons belonging to Conformer A are more tightly centered around +2.0 than are those due to the conformons belonging to Conformer C centered around −2.0.

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