Autonomic Nervous System by Daniel Pedro Cardinali

Autonomic Nervous System by Daniel Pedro Cardinali

Author:Daniel Pedro Cardinali
Language: eng
Format: epub
Publisher: Springer International Publishing, Cham


The above-mentioned mechanisms also include the peripheral portion of the ANS. From studies in the SCG territory , it can be concluded that during the augmented NE release from peripheral sympathetic nerves innervating the hypothalamic–hypophyseal unit, the modulatory role of peripheral nerve terminals is differentially exerted on the release of hypophysiotropic hormones, inhibiting the release of all pituitary hormones, except for ACTH (Fig. 5.21) [54]. In animals with chronic SCGx, both ACTH and corticosterone rhythms were suppressed. The mechanism through which peripheral sympathetic neurons are capable of modifying the function of the median eminence remains undefined. As SCG efferences play an important role in regulating the cerebral and choroidal blood flow, the outcomes of SCGx on the median eminence may represent a particularly sensitive vasomotor effect of the peripheral noradrenergic terminals. Otherwise, they may involve a more complex interrelationship, such as a direct modulatory effect on hypophysiotropic hormone release [54].

Fig. 5.21Diagram that summarizes the changes in the hypothalamic–pituitary unit after cervical sympathetic activation. SON supraoptic nucleus, PVN paraventricular nucleus, SCG superior cervical ganglion, MCG medial cervical ganglion, ICG inferior cervical ganglion. Reproduced with permission from Cardinali [21]



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