Anatomy and Physiology Made Incredibly Visual! by Janyce G. Dyer

Anatomy and Physiology Made Incredibly Visual! by Janyce G. Dyer

Author:Janyce G. Dyer
Language: eng
Format: epub
ISBN: 9781451191387
Publisher: Lippincott Williams & Wilkins
Published: 2014-04-14T16:00:00+00:00


2

Opsonization

Antibody (immunoglobulin G) or complement fragment coats the microorganism, enhancing macrophage binding to the antigen, now called an opsinogen.

3

Ingestion

The macrophage extends its membrane around the opsonized microorganism, engulfing it within a vacuole (phagosome).

4

Digestion

As the phagosome shifts away from the cell periphery, it merges with lysosomes, forming a phagolysosome, where antigen destruction occurs.

5

Release

When digestion is complete, the macrophage expels digestive debris, including lysosomes, prostaglandins, complement components, and interferon, which continue to mediate the immune response.



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