One Health: The Human-Animal-Environment Interfaces in Emerging Infectious Diseases by John S. Mackenzie Martyn Jeggo Peter Daszak & Juergen A. Richt
Author:John S. Mackenzie, Martyn Jeggo, Peter Daszak & Juergen A. Richt
Language: eng
Format: epub
Publisher: Springer Berlin Heidelberg, Berlin, Heidelberg
2.3.2 Laboratory Services and Diagnosis
Laboratory capacity building in support of diagnosis, and subsequently in the further characterization of viruses, has been a markedly successful aspect of the Indonesian response (Damayanti et al. 2004a, b; Dharmayanti et al. 2004 and Wiyono et al. 2004a, b). Biosafety considerations demanded an alternative diagnostic approach to virus isolation as the standard diagnostic approach. Real-time PCR, supported by proficiency testing and trouble shooting support, has seen the technique successfully established in all national government laboratories and more broadly. However nationally, there has not been full and effective use of this capability. The flow of specimens to laboratories has been less than that considered optimal. More submissions from the larger commercial poultry operators to the government laboratory system are necessary to allow for an ongoing comprehensive monitoring of the national situation.
Importantly, laboratory biosafety issues have been addressed to the extent possible with available facilities. Laboratory-acquired human infections have not been reported. Initial molecular analyses of isolates (Smith et al. 2006) and analyses to the present time (WHO/OIE/FAO 2012) provide evidence that Indonesia suffered only one introduction of H5N1 infection and that therefore national quarantine procedures and supporting biosafety communications have been effective.
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