Dietary Supplementation in Sport and Exercise by Hoffman Jay R.;

Author:Hoffman, Jay R.;
Language: eng
Format: epub
Publisher: Taylor & Francis Group
Published: 2019-06-15T00:00:00+00:00

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Guanidinoacetic acid in health, sport and exercise

Sergej M Ostojic

Background

Introduced to medicine and human nutrition approximately 70 years ago by Dr. Henry Borsook from Caltech, guanidinoacetic acid (GAA, also known as glycocyamine, betacyamine or N-amidinoglycine) still drives scientific attention as an intriguing energy-boosting supplement in both athletic and clinical environments. Despite the fact that GAA has been used as a dietary supplement many years before its well-known complement creatine, it still remains far less described in terms of effectiveness and safety, with only two dozen studies evaluating GAA applicability in humans. Nevertheless, recent research has evoked interest for this long-forgotten supplement, with GAA re-appearing as a potent energy-stimulating agent, consumed either as a sole preparation or co-administered with other nutrients. This chapter provides an update on GAA pharmacology, efficacy and safety in medicine, sport and exercise and an overview of possible advanced formulas that contain GAA.

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