Bacterial Pathogens and Their Virulence Factors by Douglas I. Johnson

Bacterial Pathogens and Their Virulence Factors by Douglas I. Johnson

Author:Douglas I. Johnson
Language: eng
Format: epub
Publisher: Springer International Publishing, Cham


EspG1/G2:Induces the internalization of aquaporins; affect water absorption; leads to diarrhea

Disrupts microtubules; leads to inhibition of Cl− absorption due to loss of microtubule-dependent membrane localization of the DRA Cl−/HCO3− exchanger

EspH:Functions in actin-based filopodia and pedestal formation

Blocks macrophage apoptosis

EspJ:Functions in colonization

Inhibits phagocytosis

Map:Affects Na+/H+ exchanger regulatory factor 2 (NHERF2) activity

Disrupts mitochondrial membrane potential; induces apoptosis



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