High-Field MR Imaging by Jürgen Hennig & Oliver Speck

Author:Jürgen Hennig & Oliver Speck
Language: eng
Format: epub
Publisher: Springer Berlin Heidelberg, Berlin, Heidelberg

Furthermore, ultra-high field MRI offers the opportunity to more accurately depict the fine structure of the cerebellum. Hereditary ataxias affect the cerebellar cortex and nuclei to varying degrees. In Friedreich’s ataxia and SCA3, degeneration of the cerebellar nuclei is dominant, particularly of the dentate nucleus. In the case of SCA1, SCA2, and SCA6, however, the cerebellar cortex is particularly affected. The dentate nucleus and also the other cerebellar nuclei can be depicted at very high resolution using 7 T MRI (Maderwald et al. 2009a) (Fig. 13).

Fig. 13The dentate nucleus in a healthy subject. a Axial 7 T SWI (resolution 0.5 mm × 0.5 mm × 0.5 mm). b 3D reconstruction of the cerebellar nuclei: red dentate nucleus, yellow emboliform nucleus, green globose nucleus, blue fastigial nucleus

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