Biomaterials for Tissue Engineering Applications by Jason A. Burdick & Robert L. Mauck

Author:Jason A. Burdick & Robert L. Mauck
Language: eng
Format: epub
Publisher: Springer Vienna, Vienna

10.1.3.2 Trauma

Trauma can occur due to a single excessive load, or repetitive joint overloading. Tissue damage can occur in the form of a microfracture, where the damage to the articular surface is not visible, or it can occur in the form of a visible tissue disruption of variable length. If the damage penetrates through the tidemark and into the subchondral bone it is called an osteochondral fracture [2]. Unfortunately, defects rarely repair themselves and only continue to grow worse with age. Most significant injuries to articular cartilage will result in the eventual onset of OA. The healing potential and severity of disease are dependent on the size and location of injury, as well as patient health and age [19].

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