Applications of Nanotechnology for Green Synthesis by Unknown

Author:Unknown
Language: eng
Format: epub
ISBN: 9783030441760
Publisher: Springer International Publishing

3.2 Antimycotic Agents

Biological synthesized nanoparticles have also been widely explored for their antimycotic potential against different pathogenic mycological species. Gajbhiye et al. (2009) have reported the enhanced antimycotic activity against different mycological species presented by Ag nanoparticles synthesized using fungal strain such as Alternaria alternate. Khan et al. (2018) has reported the improved antimycotic propensity of ZnO and Cu-doped ZnO synthesized by using leaves extracts of plants such as A. indicum, C. infortunatum, and C. inerme against three fungal strains such as A. flavus, A. niger, and T. harzianum. Moreover, CdS nanoparticles synthesized by using microbes have been reported for their enhanced fungicidal activity against two mycological species such as A. flavus and A. niger (Rajeshkumar et al. 2014). Several other biologically synthesized nanoparticles including CuO, Au, Ni, NiO, Pt, and Pd have been reported for their antifungal potential.

The antifungal mechanism of nanoparticles against mycological species is not cleared and well explained. However, Reidy et al. (2013) described that Ag nanoparticles present their antifungal action by attaching on the cell’s surface. From where they penetrate into the cell and interact with phosphorous containing molecular functionalities such as DNA or arrest the respiratory process of the fungal cells, which ultimately led the death of fungal cell. It also has been suggested that Ag nanoparticles can also interact with thiol (-SH) groups of enzymes and make them inactive. As a result, death of fungi cell occur (Reidy et al. 2013). All these factors contribute towards nanoparticles inhibitory action against mycological species. It can be concluded that nanoparticles antifungal mode of action is somehow similar to their antibacterial mode of action.

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