The Bethesda Handbook of Clinical Hematology, 4e by Unknown

The Bethesda Handbook of Clinical Hematology, 4e by Unknown

Author:Unknown
Language: eng
Format: epub


Table 17.4 IMWG Response Criteria

Standard Response Categories

Clinical relapse

Any one or more of following criteria: Worsening disease and/ or end-organ dysfunction related to plasma cell neoplasm Hypercalcemia (11 mg/ dL)

Decrease in hemoglobin ≥ 2 g/ dL

Rise in serum creatinine by 2 mg/ dL or more from the start of the therapy

Hyperviscosity

Relapse from complete response

Any one or more of following criteria: Reappearance of serum or urine M-protein by immunofixation or electrophoresis

Development of ≥5% clonal plasma cells

Signs of clinical relapse



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