Epi-paleo Rx: The Prescription for Disease Reversal and Optimal Health by Kruse Dr. Jack

Author:Kruse, Dr. Jack [Kruse, Dr. Jack]
Language: eng
Format: mobi, epub
ISBN: 9780989057707
Publisher: Optimized Life PLC
Published: 2013-02-20T07:00:00+00:00

3. What is quite clear is that one must eat a primal template to lower the risk of cardiac disease. This is cornerstone principle. The primary reason this diet works is because it best supports the endogenous (internal) antioxidant system without supplements, and it optimizes our thyroid status while properly regulating the generation of inflammatory cascades. Let’s dive into some science here. The Paleolithic diet is best known for advocating a low omega 6 level and a higher omega 3 level. By having an omega 6/3 ratio below 4/1, we suppress formation of PGE2 and leukotriene B4, which are both very inflammatory and destroy our hormonal responses. This is what alters our epigenetic switches. The SAD provides processed carbs and PUFAs that specifically raise this flame-throwing chemicals, driving up HS-CRP. But the Paleolithic diet lowers IL-6, TNF alpha, TNF beta, IL-1b, and IL-8, which are our first-line cytokine responses. Few test these cytokines, but each one causes very specific biochemical alterations that affect the pathways of how cells signal one another and the brain. (The most important cellular signals for us to test are the hormonal responses.) These cytokines are behind every Neolithic disease known to man. We do not test for these often because the testing is not covered by insurance and it costs a lot of money. I am hoping soon that we can abandon HS-CRP and use cytokine panels instead. They are way more sensitive and specific. We can make major predictions that are quite accurate when we know this information.

Conventional wisdom says saturated fats are a major cause of heart disease, but a very a recent meta-analysis does not favor this view. Instead, it supports a primal diet. The Harvard study, done in 2010 by Dariush Mozaffarian, M.D., showed that when the USDA recommends we replace saturated fats in our diet with carbs, heart disease is the result. The study was comprehensive and well done, and showed that replacing saturated fat with carbohydrates raised triglyceride levels and lowered HDL levels. It went further to show this dietary change did not raise or lower the ratio of total cholesterol to HDL, and suggested saturated fats play no role at all in heart disease. This data should have moved organized cardiology, or at least Dr. Oz., but it fell on deaf ears.

I suggest you use this information wisely if you have heart disease. I advocate plenty of saturated fat in my own diet. Coconut oil has been my number-one diesel fuel since 2007. Now, in 2012, I have proof that my Primal Sense was right all along. The Paleolithic diet provides for saturated fats, very low levels of PUFAs, low carbohydrate exposures, and limits most processed foods that stimulate inflammation. This is why it is a core element in the Primal Rx.

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