The Republican War on Science by Chris Mooney

Author:Chris Mooney [Mooney, Chris]
Language: eng
Format: epub
ISBN: 9780465003860
Publisher: Basic Books
Published: 2007-03-16T05:00:00+00:00

From the standpoint of understanding and ultimately curing diseases, the existing lines have yet another deficiency, as Stanford University pathologist Irving Weissman explained to me in June 2004 when we met in his office at the Stanford University School of Medicine. Ideally, Weissman explained, scientists would like to have pluripotent stem cell lines containing the genes of a diabetic, an Alzheimer’s patient, someone with cystic fibrosis, and individuals suffering from various types of cancer: a stem cell line for virtually every disease. Then, by injecting the human cells into living mice and watching them grow, scientists could observe the step-by-step evolution of the disease over the short lifespan of a mouse rather than the long lifespan of a human (one strategy for pursuing the third scientific possibility as outlined by Goldstein). “You might be able to start to understand, especially with complex genetic diseases like Lou Gehrig’s, which gene goes wrong in which order to cause that disease,” says Weissman.

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