Mechanical Ventilation by Shelledy David C.; Peters Jay I.;

Author:Shelledy, David C.; Peters, Jay I.;
Language: eng
Format: epub
Publisher: Jones & Bartlett Learning, LLC
Published: 2020-07-15T00:00:00+00:00

Oxygenation

Adequate tissue oxygenation requires adequate arterial oxygen content, sufficient cardiac output, and peripheral tissue perfusion. Arterial oxygen content (CaO2) is dependent on arterial oxygen tension (PaO2), arterial oxygen saturation (SaO2), and hemoglobin level (Hb) where:

CaO2 = 1.34 × SaO2 × Hb + 0.003 × PaO2.

Tissue oxygen delivery (ḊO2) is dependent on the arterial oxygen content (CaO2) and cardiac output (Q̇T; total cardiac output) where:

ḊO2 = CaO2 × Q̇T.

Cardiac output (Q̇T; also noted as CO) is dependent on stroke volume (SV) and heart rate (HR) where:

Q̇T = SV × HR.

Normal values for each of these variables is listed in Table 7-1.

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