Genome Sequencing and Analysis of a Porcine Delta Coronavirus from Eastern China by ${articleAuthors}

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Tags: European Journal of Experimental Biology, Porcine deltacoronavirus (PDCoV) is an enveloped, single-stranded, positive-sense RNA virus that is taxonomically classified within the family Coronaviridae, genus Deltacoronavirus [1]. The virus was first identified through a genomic sequence analysis of avian and pig isolates in Hong Kong in 2012 [2]. PDCoV was first detected in farmed pigs with diarrhea in the United States in early 2014 [3]. PDCoV causes an enteric disease that is characterized by watery diarrhea, dehydration, low mortality in adult pigs, and high mortality in piglets. The clinical symptoms of PDCoV disease are very similar to those of porcine epidemic diarrhea, but PDCoV disease is milder [4]. Since April 2017, disease caused by PDCoV strains has been reported in North America (the United States, Canada, and Mexico) [5-10] and Asia, including South Korea, Mainland China, Thailand, Laos, and Vietnam [11-17].


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