Advances in Asthma by Unknown

Author:Unknown
Language: eng
Format: epub
ISBN: 9789811327902
Publisher: Springer Singapore

The ability of FOT parameters to predict an improvement in FEV1 after ICS/LABA combination treatment was investigated in 31 untreated patients with asthma [20]. In multivariate logistic regression analyses, >10% change in FEV1 was independently predicted by R5 (adjusted odds ratio 15.9). The ROC curve analyses also revealed that the area under the curve (AUC) was higher for R5 (0.731) than for any other parameters. To detect a treatment effect or daily fluctuations, minimal clinically important differences in FOT parameters should be established.

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