Practical Guide to Dermatology by Unknown

Author:Unknown
Language: eng
Format: epub
ISBN: 9783030180157
Publisher: Springer International Publishing

◦ TNF-alpha inhibitors may halt the disease, shorten disease duration, improve mortality, and decrease SJS/TEN related adverse events.

■ Etanercept 50 mg subcutaneously once

■ Infliximab 5 mg/kg infusion once

■ Studies to date showing benefit from TNF-alpha inhibitors have had low numbers of patients

◦ Some studies show a mortality benefit from high dose IVIG (>2 g/kg total dose) but other reviews showed no such benefit

■ A large U.S. multicenter retrospective cohort study recently demonstrated benefit for IVIG when used in conjunction with systemic steroids.

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