Essential Oil Safety: A Guide for Health Care Professionals by Tisserand Robert & Young Rodney

Author:Tisserand, Robert & Young, Rodney [Tisserand, Robert]
Language: eng
Format: epub
ISBN: 978-0-7020-5434-1
Publisher: Elsevier Health Sciences UK
Published: 2013-12-01T16:00:00+00:00

Systemic effects

Acute toxicity: No information found. Acute oral LD50 in rats for tuberose concrete > 5 g/kg (Letizia et al 2000 p. S231–S233).

Carcinogenic/anticarcinogenic potential: No information found. Methyleugenol is a rodent carcinogen if exposure is sufficiently high; anticarcinogenic activity has been reported for farnesol (see Constituent profiles, Chapter 14 ).

Comments

A benzyl cyanide content of 1.0%, found only in Indian tuberose absolute, would require a maximum dermal use level of 12.5%, but this is eclipsed by the need to restrict methyleugenol. Similarly, maximum dermal use levels for isoeugenol and methyl salicylate do not apply, as they are higher than that of methyleugenol. Formerly produced by the enfleurage process, tuberose absolute is now solvent extracted, usually with petroleum ether, to produce the concrete, followed by alcohol extraction to produce the absolute (Burfield 2000 p. 381).

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