Stahl's Illustrated Substance Use and Impulsive Disorders by Stephen M. Stahl & Meghan M. Grady

Stahl's Illustrated Substance Use and Impulsive Disorders by Stephen M. Stahl & Meghan M. Grady

Author:Stephen M. Stahl & Meghan M. Grady
Language: eng
Format: mobi, azw3, epub
Publisher: Cambridge University Press
Published: 2012-10-03T21:00:00+00:00


Nicotine Gum

Nicotine gum

Nicorette

Dosage Range:

9–12 pieces per day (2 mg or 4 mg per piece)

Duration of Treatment:

Typically 6 weeks, then taper, though longer treatment may be beneficial

Advantages:

Flexible dosing

Disadvantages:

Requires frequent dosing; no food/drink 15 minutes before use; use caution in patients with dental problems or temporomandibular joint pain syndrome

FIGURE 5.8. Nicotine gum is available over the counter in strengths of 2 mg (for those who smoke less than 25 cigarettes per day) or 4 mg (for those who smoke 25 or more cigarettes per day). Nicotine absorption peaks after approximately 30 minutes with the gum, which should be chewed until a tingling sensation occurs, after which it should be “parked” between the cheek and the gum. Food or drink (acidic beverages in particular) should not be consumed for 15 minutes prior to use. A piece of gum is typically chewed every 1–2 waking hours during the first 6 weeks, after which the frequency may be tapered. No more than 30 pieces of the 2-mg dose or 20 pieces of the 4-mg dose should be chewed in a single day. Adverse effects include jaw pain, sore throat, excess saliva, oral blisters, nausea, and indigestion. In addition, the saliva should not be swallowed, as it can cause heartburn or gastrointestinal irritation. Approximately 10% of individuals using the gum develop dependence.



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