SMART PROSTHETICS: EXPLORING ASSISTIVE DEVICES FOR THE BODY AND MIND by The National Academies
Author:The National Academies
Language: eng
Format: epub
Tags: Health and Medicine : Medical Technologies and Treatments
Publisher: NATIONAL ACADEMY PRESS
Published: 2007-03-09T00:00:00+00:00
Structural Tissue Interfaces: Enabling and Enhancing Continual Maintenance and Adaptation to Mechanical and Biologic Factors
TASK GROUP DESCRIPTION
Background
Successful implantation of devices that employ a direct structural interface with native tissues and organs requires the development of an intimate and symbiotic relationship enabling effective transmission of both mechanical and biologic signals. Furthermore, these mechanical and biologic signals serve as important regulators of the structure and function of the interface tissues. As a result, long-term incorporation and maintenance of an effective structural tissue interface will depend on the delivery of âjust the rightâ signals.
From a design optimization perspective, an approach to the development of robust tissue interfaces would include the fabrication of implants that mimic the structure, mechanical properties, and biologic behavior of native tissue. An alternative strategy might include the design of an implant with generic properties that can rapidly adapt to the local environment (mechanical and biologic) by remodeling its structure and material properties. Clearly, these strategies are interrelated and depend on the creation of local niches inducing normal behavior of cells, matrices, and bioregulatory factors.
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