Criticality in Neural Systems by Schuster Heinz Georg Plenz Dietmar Niebur Ernst

Author:Schuster , Heinz Georg, Plenz, Dietmar, Niebur, Ernst [Niebur Ernst]
Language: eng
Format: epub
ISBN: 9783527651023
Publisher: Wiley
Published: 2014-03-10T00:00:00+00:00

Figure 11.2 Experimental study of excitability dynamics. An isolated neuron is stimulated with a sequence of short (400 μs) electrical pulses. Shown are extracellular voltage response traces, each 20 ms long. The traces are ordered from top to bottom, and temporally aligned to the stimulation time. For visual clarity, only every other trace is plotted. In the example shown, the neuron is stimulated with a 1-Hz sequence for 1 min (top section of the figure, 60 traces). For this stimulation protocol, the response latency is stable (arrow shows the time between stimulation and spike) and the response is reliable, implying constant excitability. The stimulation rate is then abruptly increased to 20 Hz for 2 min (middle section). After a transient period, in which latency is gradually increased (excitability decreases), the neuron reaches an intermittent steady state, in which it is barely excitable, spiking failures occur, and the response is irregular. When the stimulation rate is decreased back to 1 Hz (bottom section), the latency (excitability) recovers, and the stable steady-state response is restored.

Download

Copyright Disclaimer:
This site does not store any files on its server. We only index and link to content provided by other sites. Please contact the content providers to delete copyright contents if any and email us, we'll remove relevant links or contents immediately.